A Clinician's Guide to Pulmonary Fibrosis - Hardcoverby Kimberly Dawson (Editor) Fibrosis is refers to the excessive matrix deposition that results in the impairment of organ function and tissue destruction. It is the end result of chronic inflammatory responses brought on by a variety of stimuli such as autoimmune responses, tissue damage, persistent infections, allergic reactions and radiation. The fibrosis of lung tissue is known as pulmonary fibrosis. Some of its prominent symptoms are fatigue,